STING1 and neoplasm: Pattern recognition receptors (PRR), such as toll-like receptors (TLR), nod-Like receptors (NLRs), and cytosolic sensors such as stimulator of interferon genes (STING) involved in the sensing of pathogen-associated molecular patterns (PAMPs) and danger-associated molecular patterns (DAMPs), are responsible for tuning both myeloid activation and further polarisation of immune response towards an anti-tumour or pro-tumour phenotype [203].