DYRK2 and cancer: DYRK1A is a well-known player in nervous system-related diseases and cancer (reviewed in Boni et al., 2020; Demuro et al., 2021; Lindberg and Meijer, 2021) while DYRK2 has been mainly implicated in cancer (reviewed in Yoshida and Yoshida, 2019, 2022; Correa-Sáez et al., 2020; Lindberg and Meijer, 2021; Tandon et al., 2021).