The results of WIKI pathway analysis illustrated that LOXs converged in ALLOGRAFT REJECTION and BURN WOUND HEALING as well as inflammation- or immunity-related pathways such as COMPLEMENT SYSTEM (for LOX, LOXL2, and LOXL3), IL18 SIGNALING PATHWAY (for LOXL1 and LOXL4) and OVERVIEW OF PROINFLAMMATORY AND PROFIBROTIC MEDIATORS (for LOXL4) together with the enrichment of viral infection including EBOLA VIRUS INFECTION IN HOST (for LOXL2 and LOXL3) and NETWORK MAP OF SARSCOV2 SIGNALING PATHWAY (for LOXL4). The gene discussed is IL18; the disease is viral infectious disease.