Considering some previous investigations illustrating that LOXs, especially, LOX, LOXL1, and LOXL4 are closely associated with immunity (Tenti and Vannucci, 2020; Li et al., 2021; Tan et al., 2021), finally contributing to tumor progression, we would like to explore whether LOXs expressions were correlated with glioma immunity. Here, LOXL4 is linked to central nervous system cancer.