It is also worth noting that in a case study, a male patient with new coronary disease developed acute hepatotoxicity after receiving remdesivir and p-glycoprotein (P-gp) inhibitor treatment, which may result from the two drugs interacting with each other, and it was recommended to use P-gp with caution in the clinical treatment of remdesivir (Leegwater et al., 2021). This evidence concerns the gene PGP and coronary artery disorder.