By comparing the incidence of malaria, parasiteia levels, or the severity of malaria in children with G6PD normal and deficiency, studies conducted in Africa and other regions showed that the lack of G6PD appeared to have a protective effect on severe malaria (Rockett et al., 2014; Luzzatto et al., 2016), but the results need more data to support. This evidence concerns the gene G6PD and malaria.