(100, 300 mg/kg) could improve the syndrome of TNBS-induced colitis mice by regulating the MPO and MDA contents and the levels of pro-inflammatory (TNF-α, IL-6, L-1β, IL-12, IFN-γ, IL-2, IL-17) cytokines and anti-inflammatory cytokines (IL-4, IL-10). This evidence concerns the gene IL10 and colitis.