NLRP3 and Alzheimer disease: As the Head of the Department of Neurodegenerative Diseases and Geriatric Psychiatry at the University Hospital Bonn, and the Head of the Research Group of the German Center for Neurodegenerative Diseases (DZNE), from 2013 till today, he has continued to focus and conduct research on NLRP3 inflammasome in AD, with several high-quality publications and a significant influence in the field.