Previous studies have shown that people with normal ALT levels develop moderate liver tissue inflammation (16.8–40%) and moderate liver fibrosis (24.2–35.9%) (Ormeci et al., 2016; Tan et al., 2017; Choi et al., 2019; Liu et al., 2022), which are associated with a high risk of progression to liver cirrhosis and cancer. The gene discussed is GPT; the disease is Hepatic fibrosis.