The treatment of aortic endothelial cells with the oxysterol 7-ketocholesterol (simulating the effects of oxidized LDL) resulted in induced Eng expression and consequent increase in adhesion and transmigration of monocytes via endothelial monolayer, pointing out to a crucial role of Eng in 7-ketocholesterol-induced leukocyte transmigration and endothelial dysfunction (33). Here, ENG is linked to endothelial dysfunction.