Then, CRC samples in the TCGA database were divided into high- (n = 309) and low-risk groups (n = 310), and it was found that the 15 mRNAs, M1AP, C1QTNF4, SYT1, SEPTIN5, GRID2IP, PAQR6, NIN, DTX1, TNFRSF11 A, HOXD13, ZNF20, ALPG, RIMS3, SLC16A8, and TNNT1, had the potential to be prognostic biomarkers in CRC (Figure 4(c)). This evidence concerns the gene GRID2IP and colorectal carcinoma.