AFP and hepatocellular carcinoma: In multivariate Cox proportional hazard regression analysis, etiology (HR = 0.192, 95%CI: 0.088–0.418, p = 0.001), the AFP level (HR = 2.893, 95%CI: 1.233–6.787, p = 0.015), and vascular invasion (HR = 3.158, 95%CI: 1.436–6.942, p = 0.004) were identified as independent prognostic factors for the PFS of HCC patients.