REN and atherosclerosis: KEGG enrichment analysis showed the related cell signaling pathways in Figure 3D, of which those signals of interest were cell adhesion molecules, Rap1 signaling pathway, focal adhesion, axon guidance, PI3K-Akt signaling pathway, protein digestion and absorption, EGFR tyrosine kinase inhibitor resistance, AGE-RAGE signaling pathway in diabetic complications, cGMP-PKG signaling pathway, renin secretion, and fluid shear stress and atherosclerosis.