BLK and systemic lupus erythematosus: To test this hypothesis, we prepared capture Hi-C libraries from two 1,000 Genomes EBV-infected lymphoblastoid cell lines (LCLs), NA07000 and NA07056, both heterozygous for the SLE-associated SNP rs922483 (Guthridge et al., 2014), located in the promoter of BLK.