Key words related to KEGG enriched signaling pathways mainly include ECM-receptor interaction, Cell cycle, Viral protein interaction with cytokine and cytokine receptor, PPAR signaling pathway, PI3K-Akt signaling pathway, P53 signaling Pathway, etc. It is well known that PARP and PI3K are signaling pathways closely related to the invasion and migration of breast cancer. The gene discussed is TP53; the disease is breast cancer.