TP53 and breast carcinoma: Key words related to KEGG enriched signaling pathways mainly include ECM-receptor interaction, Cell cycle, Viral protein interaction with cytokine and cytokine receptor, PPAR signaling pathway, PI3K-Akt signaling pathway, P53 signaling Pathway, etc. It is well known that PARP and PI3K are signaling pathways closely related to the invasion and migration of breast cancer.