The sub-types of with the highest proprotion of all alterations were Hepatocellular carcinoma plus Intrahepatic Cholangiocarcinoma, Hepatocellular Adenoma, and Hepatocellular carcinoma for ATXN3, ATXN3L, JOSD1, and JOSD2, respectively (Figures 5A–E). The gene discussed is ATXN3L; the disease is intrahepatic cholangiocarcinoma.