Finally, the results suggested that eight CpG sites in ATXN3, the one CpG site in ATXN3L, 10 CpG sites in JOSD1 and the one CpG site in JOSD2 were related to the prognosis in HCC patients (Figure 8, Supplementary Figure S3, and Supplementary Table S2). The gene discussed is ATXN3L; the disease is hepatocellular carcinoma.