JOSD1 was found to be up-regulated in the head and neck squamous cell carcinoma (HNSCC) (Jing et al., 2021), gynaecological cancer (GC) cells (Wu et al., 2020), and acute myeloid leukemia (AML) cells (Yang et al., 2022). This evidence concerns the gene JOSD1 and head and neck squamous cell carcinoma.