One study, conducted in a Salmonella infection model, showed that antigen-specific B cells are capable of cross-presenting antigen to CD8+ T cells, and this cross-presentation is partially dependent on proteasomes; CD8+ T cells demonstrated decreased degranulation, as measured by CD107a expression, when CD8+ T cells were primed by proteasome-inhibited B cells (200). This evidence concerns the gene CD8A and Salmonella Infections.