IL6 and macrophage activation syndrome: Furthermore, MIS-C represents a cytokine storm induced by SARS-CoV-2 with elevated inflammatory markers, including C-reactive protein (CRP), procalcitonin, neutrophilia, lymphopenia, and pro-inflammatory cytokine levels (i.e., IL-6, IL-10, ferritin, and D-dimers), that often meets the criteria for macrophage activation syndrome (MAS) of children and shares certain characteristics with KD (3, 24, 25).