Among the predictive markers for colitis, the levels of IL-6 [6.12 pg/mL, 95% CI: (0-20.5) vs. 0 pg/mL, 95% CI: (0-0), P = 0.019], IL-22 [26.77 pg/mL, 95% CI: (0-134.5) vs. 0 pg/mL, 95% CI: (0-0), P = 0.033], and SCF [19.86 pg/mL, 95% CI: (16.93-24.16) vs. 11.47 pg/mL, 95% CI: (9.6-16.04), P = 0.026] were higher in patients with colitis compared to those without colitis (Figure 2B, Supplementary Figure 1). Here, IL22 is linked to colitis.