The most enriched pathways were DNA double−strand break repair by homologous recombination (four genes), DNA double−strand break repair by non−homologous end joining (four genes), hereditary breast cancer signaling (six genes), role of BRCA1 in DNA damage response (five genes), DNA double−strand break repair by homologous recombination (three genes), and role of CHK proteins in cell cycle checkpoint control (three genes) (Supplementary Figure S4). This evidence concerns the gene BRCA1 and breast cancer.