Inflammatory-related gene expression of the ovarian tissues results showed a dose-dependent (250–500 mgOE/kg) decrease in the mRNA expression of IL-6, IL-1α, NF-kB, TNF-α, and IL-1β by 25–65%, 55–75%, 15–40%, 30–55%, and 35–55%, respectively, compared to EV-induced PCOS group (see Figure 5). The gene discussed is IL6; the disease is polycystic ovary syndrome.