As seen in the PPI topological network (Figures 2(b) and 2(c)), 27 core targets were identified; among them, SRC, STAT3, MAPK1, AKT1, and PIK3R1 were the top five core targets that play an essential role in T2DM treatment by P. ginseng. This evidence concerns the gene PIK3R1 and type 2 diabetes mellitus.