KEGG pathway enrichment analysis obtained 95 signaling pathways (adjusted p < 0.01), mainly involved pathways in cancer (hsa05200), neuroactive ligand-receptor interaction (hsa04080), the PI3K/Akt signaling pathway (hsa04151), proteoglycans in cancer (hsa05205), the Rap1 signaling pathway (hsa04015), and the Ras signaling pathway (hsa04014). This evidence concerns the gene PIK3CA and cancer.