VEGFA and breast carcinoma: Additionally, anticancerous effect of TQ mainly occurs by modulating different cell signaling pathways such as Bcl2/Bax ratio, vascular endothelial growth factor (VEGF), p53, NF-κB, and other oncogenes [10, 11] as depicted in breast cancer models that TQ can attenuate VEGF, enhance serum INF-γ levels, and suppress angiogenesis [12].