SDC1 and diabetes mellitus: To further clarify the association between EG shedding and coronary microcirculation in patients without DM, we further analyzed the difference of syndecan-1 among patients without DM (CMD vs. non-CMD: 77.36 ± 55.27 vs. 45.9 ± 33.79 ng/ml, P < 0.01, Figure 2C; IMVC vs. non-IMVC: 73.58 ± 57.23 vs. 51.51 ± 36.92 ng/ml, P < 0.01, Figure 2D).