In the comparison of the SSc group (n = 80) and control group (n = 208), only RGPD4 on chromosome 2q12.3 met the P-value threshold criteria (0.05/18,899 = 2.51 × 10-6) (P = 1.36 × 10-6, P-FDR = 0.025, OR = 15.95). Here, RGPD4 is linked to systemic sclerosis.