Recent research on the anti-cancer effects of traditional Chinese herbal medicines has determined that Huangqin-Baishao Herb Pair and Zuojinwan have the potential to inhibit the development of CRC through the PI3K/Akt/mTOR pathway; however, the effective components that may inhibit the development of CRC have not yet been determined (93, 104). The gene discussed is PIK3CA; the disease is cancer.