Survival analysis of these prognosis-related pyroptosis genes based on the median threshold showed that 14 potential pyroptosis-related genes were significantly associated with survival in breast cancer: IGLV1-44, IGLV1-51, IGLV1-66, CALML3, IGHA2, PAK7, TNN, TP53AIP1, PCP2, TRBV7-4, EDAR, IGLV3-19, FREM1, and ZMYND10 (Figures 2B–O). This evidence concerns the gene FREM1 and breast cancer.