BCL2 and chronic myelogenous leukemia, BCR-ABL1 positive: It has been reported that the low rate of apoptosis in some cancer cells, including glioblastoma, ovarian cancer, CML and AML, may be contributed to downregulation of miR-153 which targets three antiapoptotic genes, Bcl-2, Mcl-1 and XIAP through binding to 3 ́UTR of their mRNAs (34, 36, 39).