Chimeric antigen receptor T-cell therapy (CART) targeting the CD19 antigen (1) prolongs progression-free survival (PFS) and overall survival (OS) in relapsed or refractory diffuse large B-cell lymphoma (DLBCL; 2–4), follicular lymphoma (FL; 3, 4), and mantle cell lymphoma (MCL; 5). Here, CD19 is linked to mantle cell lymphoma.