In this scenario statistically significant changes in expression due to a presence of tumor were observed for two miRNAs (Figure 8) which were downregulated in GH secreting PitNETs: miR-625-5p (Log2FC = -1.98, P = 0.0009), miR-130b-3p (Log2FC = -2.31, P = 0.0002). Here, GH1 is linked to neoplasm.