Also C-terminal missense mutations in the TARDBP gene were detected as a relatively frequent genetic underpinning of PPA-MND (29.4%), although with a disproportion toward SD (80%; PNFA: 20%) – this last finding being in line with several reports (Gelpi et al., 2014; González-Sánchez et al., 2018), also showing that SD is overrepresented in TARDBP carriers compared to other FTD phenotypes (Caroppo et al., 2016; van Rooij et al., 2020). This evidence concerns the gene TARDBP and mild neurocognitive disorder.