CHCHD2 and Parkinson disease: Drosophila models expressing human α-synuclein and human CHCHD2 T61I in a Drosophila ortholog of CHCHD2 and CHCHD10, CG5010 (also known as C2C10H)−/− background reproduced parkinsonism-like phenotypes such as motor disabilities, shortened life span, and α-synuclein aggregation in the brain (Ikeda et al., 2019).