CHCHD2 and Parkinson disease: Consistent with this observation, insoluble CHCHD2, CHCHD10, and α-synuclein were detected in the brain of a PD patient with CHCHD2 T61I mutation (Ikeda et al., 2019), and CHCHD2 T61I was also co-localized with Lewy bodies (Ikeda et al., 2019).