Notably, the ETO-family transcriptional corepressors, including ETO (also known as RUNX1T1), ETO2 (also known as CBFA2T3) and MTGR1 (also known as CBFA2T2), are all involved in leukemia-causing chromosomal translocations (Miyoshi et al., 1993; Nucifora et al., 1993; Gamou et al., 1998; Guastadisegni et al., 2010; Gruber et al., 2012; Thiollier et al., 2012). This evidence concerns the gene CBFA2T2 and leukemia.