GLIS2 and acute myeloid leukemia: ETO2-GLIS2 is produced by the newly identified inv(16)(p13.3;q24.3), which is the most common translocation in non-Down syndrome M7 subtype of AML (also known as acute megakaryoblastic leukemia, or AMKL) (Gruber et al., 2012; Thiollier et al., 2012).