Additionally, TRPC1, TRPC5, TRPM2, TRPM4, TRPM7, TRPV2 and TRPV4 can independently induce EMT in cancer cells (Chen et al., 2017a; Azimi et al., 2017; Chen et al., 2017b; Almasi et al., 2019; Liu et al., 2019b; Kudou et al., 2019; Sagredo et al., 2019; Su et al., 2019; Yang et al., 2020a; Li et al., 2020b; Zhang et al., 2021; Kato et al., 2022). This evidence concerns the gene TRPM2 and cancer.