Piezo1 enhances the migration of human gastric cancer cells by modulating the activity of Rho GTPase family members (Zhang et al., 2018), altering the expression of integrin subunits via Trefoil factor family 1 (TFF1) (Yang et al., 2014), and inducing the expression EMT-associated genes via HIF-1ɑ (Wang et al., 2021). This evidence concerns the gene PIEZO1 and gastric cancer.