Based on TCGA data, we found that GPC1 expression was upregulated in multiple cancers, including breast cancer, cervical cancer, bile duct cancer, colon cancer, glioblastoma, head and neck cancer, kidney papillary cell carcinoma, lung adenocarcinoma, and pancreatic cancer (Figure 1(a)). Here, GPC1 is linked to familial pancreatic carcinoma.