METTL14 and liver dysplastic nodule: In the high-glucose human renal glomerular endothelial cells (HRGECs), METTL14 was significantly increased compared with the normal-glucose HRGECs, and METTL14 was significantly increased in the kidney tissues of DN patients both at the mRNA and protein levels compared with the normal adjacent tissues of renal carcinoma patients (35).