However, there are no related studies on FBN2, ERO1A, and FSCN1 in COVID-19.After analysis, the above 6 genes are related to prognosis and survival, and their expression is up-regulated or down-regulated in LUAD patients with COVID-19, which can be used as effective markers for screening and grading of patients with COVID-19. This evidence concerns the gene FBN2 and COVID-19.