At the same time, the authors also demonstrated that GLUT-3 was more detectable in grade 3-4 gliomas (World Health Organization (WHO) 2021) than in grade 1-2 gliomas (WHO 2021), indicating that GLUT-3 may be predominant glucose transporter in high-grade gliomas [42]. Here, SLC2A3 is linked to central nervous system cancer.