TIGIT and ovarian carcinoma: To evaluate the results on the basis of the TCGA dataset, the researchers verified the relationship between the ICOS, TIGIT, and TNFRSF8 expression levels and patient prognosis, along with the favorable survival of the subgroup with a higher CD8A level with high ICOS/TIGIT or low TNFRSF8 expression level, by analyzing the protein expression in an independent cohort of ovarian cancer patients from Peking Union Medical College Hospital (n = 208) (Figure 8(a)–8(h)).