AHRR and chronic obstructive pulmonary disease: We used the same model to establish a logistic model using AHRR/Ahrr and KCNMB2/Kcnmb2, and COPD smoker participants can be distinguished predicted with high sensitivity (0.96) and specificity (0.97), and the auROC also reached 0.98 in our dataset, compared to normal nonsmokers (Figure 7).