Although fewer neurological disorders are reported to be linked to the mutations in CII, multiple types of mutations in SDHA, and SDHB, as well as one assembly factor SDHAF1, have been reported to cause LS or LS-like symptoms (Bourgeron et al., 1995; Birch-Machin et al., 2000; Pagnamenta et al., 2006; Jain-Ghai et al., 2013; Bezawork-Geleta et al., 2017; Kaur et al., 2020). The gene discussed is SDHA; the disease is Leigh syndrome.