Accordingly, immune‐activated M1‐type macrophages (CD11c+CD11b+F4/80+ or CD86+F4/80+CD11b+) were up‐regulated (Figure 4i,m and Figures S14–S16, Supporting Information), and a drop in secretion of immunosuppressive cytokines in G6 was observed (which promotes tumor growth, i.e., TGF‐β and IL‐10)[44] (Figure 4o). The gene discussed is ITGAM; the disease is neoplasm.