Meanwhile, PDPN silencing induced an increased rate of apoptotic cells (SNU‐1: si‐PDPNs, P = 0.00837; AGS: PDPN vector, P = 0.00604; Figure 2f) and reduced the migration (SNU‐1: si‐PDPNs, P = 0.00573; AGS: PDPN vector, P = 0.0328; Figure 2g) and invasion (SNU‐1: si‐PDPNs, P = 0.00731; AGS: PDPN vector, P = 0.0173; Figure 2h) of GC cell lines. Here, JAG1 is linked to gastric cancer.