SCUBE3 and neoplasm: Subsequently, we analyzed the relationship between these seven genes and the two clusters, as well as the correlation between these seven genes and clinical indicators (Figure 3F), IGHG2, PODXL2, LRRC17, GABRA3, SCUBE3, HLF, and RFLNB were associated with gender, tumor depth, metastatic diagnosis, margin stage, age, and status.