TNFRSF18 and colorectal carcinoma: In CRC and CRLM-derived TIL, GITR was expressed on Th (11.2% ± 1.3% and 5.8% ± 1.1%, respectively) and aTh (29.4% ± 2.4% and 16.9% ± 1.4%, respectively), whereas the highest expression was found on aTreg (54.5% ± 2.5% and 42.8% ± 2.5%, respectively) (Figure 2C and D).