Phosphorylation-dependent inactivation of GSK3β also occurs during normal chlamydial infection and causes the accumulation of c-Myc protein, as GSK3β leads to a destabilization of c-Myc by phosphorylation on the threonine 58 and proteasomal degradation (AlZeer et al., 2017; Albert et al., 1994). Here, GSK3B is linked to chlamydia trachomatis infectious disease.