Rare (Purcell et al., 2014; Wang et al., 2022) and structural (Song et al., 2018) variants in CACNA1C have also been reported in psychosis, and rare variants in CACNA1C and CACNA1D identified in other neurodevelopmental syndromes (Pinggera et al., 2015; Ortner et al., 2020; Rodan et al., 2021). The gene discussed is CACNA1C; the disease is psychotic disorder.