The mADS group compared with POMS group more often included patients with acute disseminated encephalomyelitis (ADEM; 61% vs. 0% and 40% vs. 0%, respectively, both p < 0.001) and more often included myelin oligodendrocyte glycoprotein antibody (MOG-ab) seropositive patients (27% vs. 0% (p = 0.018) and 33% vs. 0% (p = 0.001), respectively), tested by cell-based assay. Here, OMG is linked to acute disseminated encephalomyelitis.