MYCN and ependymoma: The 3 anatomical locations for ependymomas as per 2021 WHO classification involve the supratentorial area where ependymomas can be sub-grouped in Zinc Finger Translocation Associated (ZFTA) fusion-bearing or Yes Associated Protein 1 (YAP-1) fusion-bearing, the posterior fossa where ependymomas are divided in Posterior Fossa A (PFA) and PFB groups, and the spinal compartments where ependymomas are observed to have an MYCN amplification [4].