IDH3A and glioma: In this context, the most recent Central Nervous System 5 (CNS5) World Health Organization (WHO) classification has divided gliomas,glioneuronal and neuronal tumors into 6 different groups, distinguishing the adult-type diffuse gliomas, which comprise Isocitrate Dehydrogenase (IDH)-wild type glioblastomas (GBs), the pediatric-type diffuse low-grade and diffuse high-grade gliomas, the circumscribed astrocytic gliomas, the glioneuronal and neuronal tumors and the ependymomas [4].