For patients with reduced LV function, all-cause mortality was higher for those who had a DCM genetic variant (1 with BAG3, 1 with LMNA, 2 with MYH7, 2 with TTN) compared those with no variant (17.6% versus 4.2%; OR, 5.0 [95% CI, 1.8–13.8]; P=0.004). Here, MYH7 is linked to familial dilated cardiomyopathy.