Oral supplementation of A. muciniphila in Apolipoprotein E knockout mice (ApoE−/−) model to study the endothelial dysfunction along with atherogenesis, has shown the reduction in the metabolic endotoxemia-induced inflammatory chemokines, such as ICAM-1, MCP-1, and TNF-α on the endothelium [10]. Here, APOE is linked to endothelial dysfunction.